Considering EBO2 therapy in London? EBO2 stands for extracorporeal blood oxygenation and ozonation: a procedure in which blood circulates through equipment outside the body before being returned. In Zen Healthcare’s introductory video, the process combines filtration, oxygen and ozone exposure, and a light-treatment stage.
This guide explains the procedure described in the video, how to interpret the proposed benefits, and the questions to ask before considering treatment. EBO2 is invasive, and the claims discussed in the video should not be taken as proof that it treats disease, improves performance or extends life.
Watch: an introduction to EBO2
Zen Healthcare introduces EBO2 and describes the stages of the procedure.
What is EBO2 therapy?
“Extracorporeal” means outside the body. EBO2 uses an external blood circuit, with blood drawn through venous access, processed and returned. You may also encounter the terms EBO and EBOO. Terminology and protocols can vary, so ask which equipment and procedure a clinic uses.
The video compares the external circulation process to dialysis. That comparison describes the setup; it does not mean EBO2 performs the same medical function or has the same evidence base as dialysis.
How does the EBO2 process work?
1. Blood passes through a filtration system
The first stage described in the video passes blood through a membrane within a closed circuit. Filtration is part of the procedure, but the presence of a filter does not by itself demonstrate clinically meaningful removal of microplastics, heavy metals or inflammatory substances. Any such claim needs evidence for the specific device, substance and patient outcome.
2. Blood is exposed to oxygen and ozone
The video then describes exposure to a medical oxygen–ozone mixture. Oxygen and ozone are different substances; ozone is chemically reactive. The presenter discusses mitochondria, cellular energy and NRF2, a pathway involved in cellular responses to oxidative stress. These proposed mechanisms do not establish that EBO2 produces a meaningful health benefit in patients.
3. A light-treatment stage is added
The system described in the video also exposes circulating blood to six wavelengths of light. The presenter links this stage to cellular energy and repair. Evidence about other forms of light therapy cannot automatically be applied to light treatment of blood within an EBO2 circuit.
How long does a session take?
The video describes approximately 45 minutes of processing, with around 4–6 litres of blood circulated through the system. This refers to circulation over the session, not that amount being removed and held outside the body at once. Consultation, preparation, monitoring and aftercare can make the appointment longer. Confirm the expected duration with the clinical team.
EBO2 benefits: separating interest from evidence
The video discusses interest in EBO2 for sports recovery, persistent health concerns and longevity. Reports of feeling better after a procedure cannot establish that the procedure caused the improvement or predict another person’s experience.
In particular, the video does not establish EBO2 as an effective treatment for Lyme disease, ME/CFS or Long COVID. It also does not establish reliable improvements in athletic performance, removal of a harmful “toxin burden”, or a longer lifespan. Persistent symptoms deserve an appropriate medical assessment and condition-specific care.
In the UK, the Advertising Standards Authority has upheld a complaint about unsupported IV ozone therapy claims, including improved energy and anti-inflammatory or antimicrobial effects. This underlines why proposed mechanisms and testimonials should be distinguished from demonstrated clinical outcomes.
Safety and suitability: what should you ask?
EBO2 requires venous access and blood handling outside the body. Ask about bleeding, infection, damage to blood cells, clotting, reactions to any medicines used, and how equipment-related complications are prevented and managed. A sterile circuit does not make an invasive procedure risk-free.
For context, UCLH’s information on plasma exchange explains risks associated with intravenous access, including infection and bleeding. Plasma exchange is a different procedure: its safety record and benefits cannot be assumed to apply to EBO2.
Before making a decision, ask your clinician:
- What evidence supports this exact procedure for my health concern?
- How do my medical history, medicines and blood-test results affect suitability?
- What are the alternatives, including not having the procedure?
- What device is used, what is its UK regulatory status, and who supervises treatment?
- What will the full appointment cost, and how will outcomes and adverse effects be reviewed?
Frequently asked questions
Is EBO2 the same as standard ozone therapy?
Not necessarily. The video describes a circulating blood-processing system with filtration and light exposure. Other ozone protocols use different equipment and blood volumes. The treatment name alone does not define the procedure or demonstrate that one version is more effective.
Is EBO2 FDA-approved?
EBO2 should not be described as an FDA-approved disease treatment. In a 2025 warning letter, the FDA identified unapproved-device violations involving a manufacturer’s EBOO and ozone/UV blood-treatment devices. That letter concerns specific US products; it does not determine the regulatory status of equipment used by Zen Healthcare. UK patients should ask about the particular device used locally.
Can EBO2 replace my existing treatment?
No. Do not stop prescribed medication or delay investigation of symptoms to pursue EBO2. Discuss any proposed procedure with the clinician responsible for your current care.
Where can I enquire about EBO2 therapy in London?
Zen Healthcare lists EBO2 at its Knightsbridge clinic. Visit the EBO2 therapy page at Zen Healthcare London for service information, or contact the team below to ask about a consultation, suitability and current availability.
Speak to Zen Healthcare
Have questions after watching the video? Send an enquiry to discuss the procedure, its limitations and whether a medical consultation would be appropriate for your concerns.
This article is for general information and does not provide a diagnosis or personalised medical advice. Treatment decisions require an individual assessment with a qualified healthcare professional.

